TB-500
A synthetic peptide fragment of Thymosin Beta-4, a naturally occurring 43-amino acid protein found throughout human and animal cells. The active region of Thymosin Beta-4 responsible for many of its biological effects has been isolated as the shorter synthetic sequence TB-500, which is studied for its role in tissue repair and cellular regeneration.

Research Focus

Promotion of cell migration and angiogenesis (new blood vessel formation).

Regulation of actin dynamics and cytoskeletal organization.

Support for tissue repair and wound healing in soft tissue models.

Investigation into cardiac and vascular recovery mechanisms.

Exploration of inflammation modulation and regenerative signaling.

Mechanisms Under Study

Actin regulation enabling cellular movement and structural remodeling.

Enhancement of angiogenic and regenerative pathways in injured tissue.

Modulation of inflammatory responses to support healing and recovery.

Product Information

Supplied as a lyophilized sterile powder.

Third-party verified for purity, molecular identity, and composition.

For laboratory research use only, not for human or animal use.

CAS Number: 77591-33-4
Chemical Formula: C₂₁₂H₃₅₀N₅₆O₇₈S
Molecular Weight: 4963.49 g/mol
Peptide Sequence: Ac-Ser-Asp-Lys-Pro-Asp-Met-Ala-Glu-Ile-Glu-Lys-Phe-Asp-Lys-Ser-Lys-Leu-Lys-Lys-Thr-Glu-Thr-Glu-Ala-Glu-Asn-Pro-Leu-Asp-Met-Glu-Ile-Ala-Gln-Glu-Lys-Phe-Asp-Ser-Lys-Leu-Lys-Lys-Thr-Glu-Thr-Glu-Ala-Glu-Asn-Pro-Leu-NH2
Synonyms: Thymosin Beta-4 Fragment, Tβ4 Synthetic Analog, TB500
Form: Lyophilized powder
Appearance: White to off-white solid