Melanotan II
A synthetic analog of alpha-melanocyte-stimulating hormone (α-MSH), developed to study how activation of the melanocortin system influences pigmentation, metabolism, and cellular protection. Melanotan II mimics the structure of α-MSH and interacts with several melanocortin receptors (MC1R, MC3R, MC4R, MC5R) involved in pigmentation, appetite, energy balance, and sexual function.

Research Focus

• Regulation of melanin synthesis and skin pigmentation.
• Mechanisms of UV response and photoprotection.
• Study of energy metabolism and appetite control via melanocortin signaling.
• Exploration of anti-inflammatory and cell-protective pathways.
• Analysis of receptor-specific peptide signaling in experimental models.

Mechanisms Under Study

• Melanocortin receptor activation (MC1R–MC5R) and downstream effects.
• Modulation of metabolic and inflammatory pathways.
• Controlled melanin production as a model for studying cellular response to stress and radiation.

Product Information

• Supplied as a lyophilized sterile powder.
• Third-party verified for purity, molecular identity, and composition.
• For laboratory research use only, not for human or animal use.

CAS Number: 121062-08-6
Chemical Formula: C₅₀H₆₉N₁₅O₉
Molecular Weight: 1024.18 g/mol
Peptide Sequence: Ac-Nle-Asp-His-D-Phe-Arg-Trp-Lys-Pro-Val-NH₂
Synonyms: MT-II, Melanotan 2, Melanotan II acetate, Melanocortin analog
Form: Lyophilized powder
Appearance: White to off-white solid