MOTS-c
A naturally occurring mitochondrial-derived peptide composed of 16 amino acids, encoded within the Mitochondrial Open Reading Frame of the 12S rRNA type-c. Unlike most peptides produced from nuclear DNA, MOTS-c originates from mitochondrial DNA, where it helps regulate energy metabolism and cellular adaptation to stress.
Research Focus
- Regulation of cellular energy balance and metabolic signaling.
- Influence on glucose and fatty acid utilization for energy production.
- Activation of pathways that support metabolic homeostasis under stress.
- Study of mitochondrial-to-nuclear communication mechanisms.
- Investigation into exercise signaling and age-related metabolic changes.
Mechanisms Under Study
- Modulation of AMPK and related energy-sensing pathways.
- Coordination of mitochondrial signaling during oxidative or physical stress.
- Cellular adaptation to metabolic demand and nutrient availability.
Product Information
- Supplied as a lyophilized sterile powder.
- Third-party verified for purity, molecular identity, and composition.
- For laboratory research use only, not for human or animal use.
